LOB

Line-of-business (LOB) manager = Руководитель направления

Eyefuck / Clusterfuck

Eyefuck - To look at someone disrespectfully or in anger

а это из слэнга
еще бывает
Clusterfuck - A combination of things going extremely wrong in a short period of time within the same general activity

Offer / Bid / Proposal

“Offer” means a response to a solicitation that, if accepted,
would bind the offeror to perform the resultant contract.
Responses to invitations for bids (sealed bidding) are offers
called “bids” or “sealed bids”; responses to requests for proposals
(negotiation) are offers called “proposals”; however,
responses to requests for quotations (simplified acquisition)
are “quotations,” not offers. For unsolicited proposals, see
Subpart 15.6.

“Solicitation” means any request to submit offers or quotations
to the Government. Solicitations under sealed bid procedures
are called “invitations for bids.” Solicitations under
negotiated procedures are called “requests for proposals.”
Solicitations under simplified acquisition procedures may
require submission of either a quotation or an offer.

Источник: Federal Acquisition Regulation at https://www.acquisition.gov/far/

In this capacity

OMB develops and executes a government-wide management agenda that includes information technology, financial management, procurement, performance, and human resources. In this capacity, OMB oversees agency management of programs and resources to achieve legislative goals and Administration policy. It also oversees agency program evaluation activities to determine their net effects, success or failure, and how agencies respond to these findings by making management improvements and developing new budget and policy proposals.

хорошее словосочетание... что-то вроде "в этой области, в этом амплуа, в этой связи"

Языковой портал Майкрософт

При локализации интерфейсов всегда опираюсь на Языковой портал Майкрософт:
http://www.microsoft.com/language/ru/ru/default.mspx
Например, термин "push".

Майкрософт туда вывел удобный поиск по своим глоссариям, которые раньше были доступны в режиме Excel.

Game-changing

game-changing (not comparable)
(sports) сritical and having the potential to alter the overall outcome.
Ex.: Our plan to transition from products to solutions is a game-changing moment for our company.
http://en.wiktionary.org/wiki/game-changing

Game-changing problem - критическая проблема
Game-changing moment - поворотный / решающий момент